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supreme - (of authority or an office, or someone holding it) superior to all others

In Iran, the Ayatollah is the supreme ruler who controls the country's population.

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substantial - Of considerable importance, size, or worth; or strongly built or solid in structure.

They named the building after him because he made a substantial donation to the charity.

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mission - A journey or action taken for a particular purpose, often of importance.

The rescue team was sent on a mission to save the trapped hiker.

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stature - The quality or state of being important or admired based on achievements or reputation

The stature of the company has increased significantly since it went public

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ramifications - The possible results of an action

Being Aristotle's student, Alexander the Great was able to plan out a military strategy taking into account all its ramifications.

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centrality - The state of being central in location or focus.

The centrality of the town square made it a perfect meeting spot.

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indispensable - Impossible to replace or substitute due to its significance.

Water is indispensable for human survival.

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legitimacy - The state of being accepted as valid, authentic, or justified; the quality of being lawful in accordance with established rules.

Many people doubted the legitimacy of the online news article because it lacked credible sources.

noun

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zenith - The highest point that something can reach.

When the soccer player was at his zenith, he helped his team win one game after another.

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crux - A vital or decisive point that determines the outcome.

Understanding the crux of the problem helped them find a quick solution.

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landmark - Characterized by an event, discovery, or change that marks an important turning point in events.

The Supreme Court decsion Brown vs. Board of Education in 1954 was a landmark case in the progress towards desegration and civil rights.

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transcendent - Extremely great, and ​going beyond the usual limits

John and Esther loved going to Beethoven concerts, because they were always rewarded with a transcendent experience.