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mercurial - Changing emotions suddenly and often

Fred loved almost everything about his wife except her mercurial behavior, where her moods changed suddenly between sadness and happiness, or love and anger

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hysterical - Having uncontrolled extreme emotion

When Amy found out that her house had been destroyed by the tornado, she broke down into hysterical crying, and could not be comforted for hours.

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deranged - Behaving in an uncontrolled or dangerous way because of mental illness

Charles Manson led a group of followers who became mentally deranged as a result of taking too many psychedelic drugs

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bonkers - Mentally unbalanced, mad and crazy, usually meant humorously

There were many long stretches of time that Joan was cooped up in the house with her kids, and it was making her go bonkers.

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catatonic - Appearing to be in a daze or stupor; unresponsive, not moving or reacting.

His experiment with psychodelics left him in a catatonic state where he showed almost no emotion, and it that took years for him to recover.

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unhinged - Mentally unbalanced and unstable

Trevor crossed the street when he saw the unhinged person yelling at him.

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delusional - Seeing or believing things that are not real

Betty was confident that she would be a millionaire by the time she would be 25, but her friends thought she was delusional.

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nuts - Crazy, insane, or stupid, often in a humorous way

Bill's friends thought he was nuts for swimming in the middle of the winter.

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crackpot - A slightly strange or foolish person

Wearing mismatched clothing and yelling to nobody in particular, the crackpot was amusing and ignored by the people who passed him by.

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loony - Crazy or silly

The patients in the mental hospital could be described as loony, but the doctors tried to treat them as normal human beings with normal problems in order to try to help them get better.

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loudmouth - Someone who speaks loudly and without thinking, often causing trouble or embarrassment.

Even though he was a real loudmouth, always bragging about his achievements and rarely listening to others, he was still amazingly successful.

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blabbermouth - An overly talkative person who speaks without thinking.

Don't tell Jerry things you don't want others to know about, because you can’t trust a blabbermouth with secrets.