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funk - A state of depression

Daryl was in a deep funk after losing his job and girlfriend in the same week.

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Misery - A state of great suffering or unhappiness, especially caused by emotional or physical pain.

After losing his job and home, he lived in deep misery for a long time, but with great effort, he slowly recovered.

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gripe - To complain about something that is bothering you

Tom griped about his power bill to the utility company because it was three dollars higher than usual.

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grouchy - Irritable, bad-tempered, and complaining

Eli was a grouchy man who hated when the neighborhood kids would walk on his lawn.

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despair - Having no hope that things will get better.

Alan sank into a despair that he could not overcome by himself, so he went to a therapist.

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doldrums - A state or period of inactivity, stagnation, or depression

It seemed that every month, Cathy sank deeper into the doldrums, and she seemed unable to do anything to snap herself out this condition.

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grumpy - Easily irritated and bad-tempered, usually from lack of sleep or feeling old

Howard's grumpy neighbor never said hello whenever Howard walked by his neighbor's house.

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cranky - Easily irritated or annoyed

New parents tend to lose sleep because they have to calm their cranky babies.

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bereft - Feeling the loss of being without something

During the war, Amal had lost all his money, possessions, and friends, and he was almost felt bereft of hope.

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wistful - Having or showing a feeling of vague or regretful longing

Sipping her coffee after a hard day's work, Becky was wistful about her life before all of the stress.

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remorse - Deep regret or guilt for a wrong committed

Serving a life sentence, Henry had plenty of time to feel remorse for his crime.

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apologetic - Feeling or showing that you are sorry for doing something wrong or for causing a problem

When Bill realized that his mistake caused the company to lose millions of dollars, he wrote his manager an apologetic email.