bonkers -
Mentally unbalanced, mad and crazy, usually meant humorously
There were many long stretches of time that Joan was cooped up in the house with her kids, and it was making her go bonkers.
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adjective
delusional -
Seeing or believing things that are not real
Betty was confident that she would be a millionaire by the time she would be 25, but her friends thought she was delusional.
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adjective
unhinged -
Mentally unbalanced and unstable
Trevor crossed the street when he saw the unhinged person yelling at him.
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batty -
Mad and slightly crazy, usually in a humorous way
The computer system wouldn't let Greg log on or change his password, and it was driving him batty.
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nuts -
Crazy, insane, or stupid, often in a humorous way
Bill's friends thought he was nuts for swimming in the middle of the winter.
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wacky -
Something that is strange and different to the point of amusement.
George’s grandmother was well known and loved for her wacky taste in shoes.
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noun
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Compulsion -
A strong, irresistible urge to do something, often against one's better judgement.
His gambling problem stemmed from a deep psychological compulsion.
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adjective
hysterical -
Having uncontrolled extreme emotion
When Amy found out that her house had been destroyed by the tornado, she broke down into hysterical crying, and could not be comforted for hours.
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adjective
loony -
Crazy or silly
The patients in the mental hospital could be described as loony, but the doctors tried to treat them as normal human beings with normal problems in order to try to help them get better.
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berserk -
To behave in a wild and uncontrolled way as a result of something unexpected happening.
When Anne found out that she had lost all her money as a result of stock fraud, she went berserk, running around the house, screaming and breaking dishes.
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daffy -
Silly, different, strange, and funny
Fred had a twirled mustache and wore an oddly colored suit, but the town's residents simply viewed him as daffy instead of someone to be afraid of.
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kooky -
Strange and different, in a funny way
Salvador Dali's kooky appearance was only exceeded by his even more bizarre paintings.