When Amy found out that her house had been destroyed by the tornado, she broke down into hysterical crying, and could not be comforted for hours.
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crank -
Someone who others think has unusual ideas or behaves strangely
Bill was seen as crank by his friends, because of the way he always spoke of the dangers of eating meat and being vaccinated.
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loony -
Crazy or silly
The patients in the mental hospital could be described as loony, but the doctors tried to treat them as normal human beings with normal problems in order to try to help them get better.
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loudmouth -
Someone who speaks loudly and without thinking, often causing trouble or embarrassment.
Even though he was a real loudmouth, always bragging about his achievements and rarely listening to others, he was still amazingly successful.
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berserk -
To behave in a wild and uncontrolled way as a result of something unexpected happening.
When Anne found out that she had lost all her money as a result of stock fraud, she went berserk, running around the house, screaming and breaking dishes.
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catatonic -
Appearing to be in a daze or stupor; unresponsive, not moving or reacting.
His experiment with psychodelics left him in a catatonic state where he showed almost no emotion, and it that took years for him to recover.
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kooky -
Strange and different, in a funny way
Salvador Dali's kooky appearance was only exceeded by his even more bizarre paintings.
adjective
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unhinged -
Mentally unbalanced and unstable
Trevor crossed the street when he saw the unhinged person yelling at him.
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lunacy -
Stupid or crazy ideas or behavior that is likely to have bad results
When Edwin Hubble suggested in 1922 that most of the little dots in the sky are entire galaxies, most scientists thought that the idea was sheer lunacy.
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daffy -
Silly, different, strange, and funny
Fred had a twirled mustache and wore an oddly colored suit, but the town's residents simply viewed him as daffy instead of someone to be afraid of.
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lunatic -
A person who is crazy
Martha was a defensive driver, to be safer with regards to a possible lunatic behind the wheel of another car.
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psycho -
A person with severe mental health issues, often describing someone who behaves in an erratic or dangerous manner.
She accused him of being a psycho and told him to leave after he repeatedly showed up uninvited and acted innappropriately.