anguish -
Severe mental or physical pain or suffering
With her personal and professional life in disarray, Jenny's anguish was often too much for her to bear.
noun
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pang -
A sudden sharp pain or painful emotion
The year was 1900, and Dmitri felt a pang of nostalgia and regret as he boarded the boat for America, knowing that he would probably never see his 'old world' again.
verb
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torment -
Cause to experience severe mental or physical suffering
William enjoyed tormenting his younger sister until she would run away and complain to their mother.
noun
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shackles -
A device, such as a chain or cuff, designed to physically limit or control a person or thing's movement.
Shackles were placed on the prisoner's feet so that he would not be able to run away and escape.
noun
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burden -
something you carry or withstand with much difficulty.
Financial debt can be a huge burden on families.
adjective
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impoverished -
Very poor.
We can hardly imagine how impoverished the average person was during the Middle Ages.
verb
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plague -
To cause constant worry, annoyance, or distress, often by repeatedly confronting someone with problems or challenges.
She was plagued by constant headaches, making it hard for her to focus on her work.
verb
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wince -
To give a slight involuntary grimace or shrinking movement of the body out of or in anticipation of pain or distress
Tiger winced as he realized he had hit the ball too far beyond the hole.
adjective
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tragic -
Something very sad often involving suffering.
The story of how Oedipus mistakenly killed his father and married his mother is a tragic story.
noun
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throes -
Intense or violent pain and struggle, especially accompanying birth, death, or great change
Samantha experienced agonizing pain during the throes of childbirth.
noun
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inflammation -
A physical condition characterized by redness, heat, swelling, and pain, often as a response to injury or infection.
The redness of the big toe was caused by an infection, and the inflammation was visible and painful.
noun
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plight -
A difficult or unfortunate situation, often one that involves hardship or adversity.
The community came together to help improve the plight of the homeless during the harsh winter months.
