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adjective

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tragic - Something very sad often involving suffering.

The story of how Oedipus mistakenly killed his father and married his mother is a tragic story.

adjective

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grueling - Extremely tiring and demanding

Troops go through grueling training before they can finally serve their country.

noun

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throes - Intense or violent pain and struggle, especially accompanying birth, death, or great change

Samantha experienced agonizing pain during the throes of childbirth.

verb

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writhe - Make continual twisting, squirming movements or contortions of the body

The soccer player writhed in pain on the ground after spraining his ankle.

noun

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agony - Extreme physical or mental suffering

Max was in physical agony as he rode his bicycle up the long mountain trail, but spiritually and emotionally he was in heaven.

noun

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plight - A difficult or unfortunate situation, often one that involves hardship or adversity.

The community came together to help improve the plight of the homeless during the harsh winter months.

nounverb verb

See noun

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torment - Cause to experience severe mental or physical suffering

William enjoyed tormenting his younger sister until she would run away and complain to their mother.

adjective

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afflicted - Suffering from a serious problem, illness, or pain, be it mental or physical.

Many people are afflicted with anxiety in high-pressure situations.

noun

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ordeal - A painful or horrific experience, especially a protracted one

Knowing it was a fight to the death, the gladiator realized that this was an ordeal he would have to overcome if he wanted to survive.

noun

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angst - A feeling of deep anxiety or dread, typically an unfocused one about the human condition or the state of the world in general

Edvard Munch's famous painting, "The Scream," is often viewed as an expression of angst in an uncertain world.

nounverb noun

See verb

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torment - Severe physical or mental suffering

Sufferers of depression must deal with the torment of their own thoughts on a regular basis.

noun

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inflammation - A physical condition characterized by redness, heat, swelling, and pain, often as a response to injury or infection.

The redness of the big toe was caused by an infection, and the inflammation was visible and painful.