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grueling - Extremely tiring and demanding

Troops go through grueling training before they can finally serve their country.

verb

See noun

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plague - To cause constant worry, annoyance, or distress, often by repeatedly confronting someone with problems or challenges.

She was plagued by constant headaches, making it hard for her to focus on her work.

noun

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hardship - Severe suffering or difficulty caused by lack of necessities like food, money, or shelter.

Many families are facing economic hardship due to rising living costs.

noun

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cramps - A painful, involuntary contraction of muscles

When Sharon got cramps in her stomach after eating the fish, she suspected that it may have been spoiled.

noun

See verb

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torment - Severe physical or mental suffering

Sufferers of depression must deal with the torment of their own thoughts on a regular basis.

adjective

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agonizing - Something that causes great physical or mental pain.

After she took the final exam, it was agonizing to her that for a whole week she wouldn't find out the results.

noun

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pang - A sudden sharp pain or painful emotion

The year was 1900, and Dmitri felt a pang of nostalgia and regret as he boarded the boat for America, knowing that he would probably never see his 'old world' again.

noun

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anguish - Severe mental or physical pain or suffering

With her personal and professional life in disarray, Jenny's anguish was often too much for her to bear.

noun

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inflammation - A physical condition characterized by redness, heat, swelling, and pain, often as a response to injury or infection.

The redness of the big toe was caused by an infection, and the inflammation was visible and painful.

adjective

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humiliated - To feel ashamed after someone embarrasses you in front of others.

When Jim revealed to everyone at the party that Marty hadn't even finished 6th grade, Marty felt humiliated.

noun

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angst - A feeling of deep anxiety or dread, typically an unfocused one about the human condition or the state of the world in general

Edvard Munch's famous painting, "The Scream," is often viewed as an expression of angst in an uncertain world.

noun

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throes - Intense or violent pain and struggle, especially accompanying birth, death, or great change

Samantha experienced agonizing pain during the throes of childbirth.